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Study design: Hospital records (1988 1999) of the index pregnancy were reviewed at caesarean delivery for oxytocine use, indication for caesarean, dilatation of cervix, speed of dilatation, duration of contractions and birth weight.
Outside the controlled environment of clinical trials, several variables may affect the pharmacodynamics of a particular drug, including dosage, duration of use, indication, comorbidities, and use of concomitant medications.
Consequently, we were unable to use indication to further restrict our study cohort.
Firstly, we did not use indication specific dose estimates for fluoroscopy and radiography.
Biases that can result in confounding effects include drug use indication bias, prevalent user bias, detection bias, and time-related biases.
Drug use indication bias and prevalent user bias may be possible when assessing these associations using cross-sectional health survey data (40).
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For example, the statement in the ICHS6, "for those biopharmaceuticals intended for chronic use indications, studies of 6 months duration have generally been appropriate…"; is this still relevant?
This single-center retrospective study was designed to assess the use (indications, efficacy, and side effects) of anti-TNF-α agents in noninfectious uveitis.
The rationale use of these agents is hindered by a lack of data concerning drug scheduling, duration of use, indications for initiation and cessation [ 9].
Between-group differences in sex ratio, anti-ulcer drug use, indications for LDA therapy, and tertile CE scores were analyzed by Fisher's exact test.
Patients on herbal remedies were asked about the history of herbal use, indications, frequency and if their healthcare providers were aware of this.
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