Sentence examples for use in a substantial from inspiring English sources

In addition, the complexity of cisplatin administration prohibits the use in a substantial proportion of patients, particularly elder patients and those with relevant comorbidities.

Tricyclic antidepressants are the mainstay of treatment of painful polyneuropathy but cannot be used in a substantial number of patients.

The scale has been used in a substantial amount of research and has been compared to Antonovsky's original 29-item measure of SOC, showing a correlation of r = 0.72 between the two measures [ 33].

They are justified only if their use results in a substantial improvement that can be evaluated in relation to cost.

This suggests that currently available drugs could be used effectively in a substantial subset of patients.

Lack of compliance in use is a substantial problem everywhere among elderly and child hearing aid users, including those in developing countries [ 13], and it is not sure whether our assumptions is realistic.

Students' dissertation research will use statistical methods in a substantial way.

On the other hand, because of the added expense of MRI, its general use could result in a substantial increase in the cost of neurological care.

A pneumococcal conjugate vaccine covering the seven serotypes most prevalent in IPD (4, 6B, 9V, 14, 18C, 19F and 23F; PCV7) has been available since 2001, and its use has resulted in a substantial reduction of vaccine type IPD in several countries where childhood vaccination programs were initiated [ 2- 5].

As the largest single user of coal, any cuts China makes in coal use have a substantial impact on global emissions.

Finally, inhibition of DNMTs in rd1 organotypic retinal explants using decitabine resulted in a substantial reduction of photoreceptor cell death, suggesting inhibition of DNA methylation as a potential novel treatment in RP.