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Our method appears to be a promising and scalable way to use existing datasets to predict environmental associations between genes and disease.
Collection of a database of normal samples from multiple tissue sites will be needed to use ISOpure; however, as shown by our deconvolution of the Director's Challenge cohort of 443 samples, deconvolution can even use existing datasets of normal samples, if the collection protocol and platform are sufficiently similar.
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"It's about citizens working with public servants to design public services, using existing datasets or datasets that we've just revealed to the world for the first time".
Such assessment can be performed using existing datasets of crashes, pedestrian counts, and automobile traffic flows to identify intersections or corridors characterized by elevated collision risks to pedestrians.
Using existing datasets, we show experimentally that it is possible to identify the presence of existing and unknown botnets activity with high accuracy even with very small time windows.
With big data repositories becoming more prevalent, using existing datasets that are related to, but not exactly the same as, a target domain of interest makes transfer learning solutions an attractive approach.
A novel catchment characterisation system was developed, in which broad-scale landscape characteristics were quantified using existing datasets, types of sediment supply feature were identified in a field survey and their distribution across the catchment was quantified using a survey of air photographs.
By developing a methodology that uses existing datasets to locate GDEs, this assessment addresses that knowledge gap.
In addition, a relationship between gene expression and copy number, and the presence of mutations in ovarian cancer was examined using existing datasets.
109 To inform our sample size calculations we used existing datasets from relevant populations.
In the short term, desk-based testing and validation of indicator definitions using existing datasets (from LMIC) is required.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com