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With the wide variation in real-world use, evaluating the whole practice best assesses overall benefits and risks.
Guideline implementation is quite complex, involving multiple stages including creating actionable products, adapting them to local context, assessing barriers, selecting and applying interventions, monitoring use, evaluating outcomes, and sustaining use [ 25].
Recently episode analysis has been used as an important tool for estimating costs, determining patterns of use, evaluating outcomes of care, and understanding medical practice variation [ 13- 15], using the entire duration of care as the basis for measurement, with the assumption that this will be more effective than counting single outpatient visits or single hospitalizations [ 13, 14, 16].
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