Moreover, the slender hepatic stage of Plasmodium (that is, the sporozoite) might not need to loosen the cell cortex to the extent that the Toxoplasma bulky tachyzoite does, or/and might use different pathways to this end, such as proteolysis of key actin-membrane adaptors.
There are some known cases where different organisms synthesize the same compounds using different pathways with different number of steps.
The above limitations are widespread and would ultimately prevent a thorough investigation of the origin and evolution of key regulators of development that may have shaped the evolution of angiosperms using different pathways such as sub or neo-functionalization [37].
This is of special pathophysiological relevance because degeneration of the neuronal soma and its processes has been demonstrated to use different molecular pathways, both of which seem to be beneficially influenced by rho kinase inhibition.
We found that all examined pathways can participate in ERK activation but that different xenoestrogens use different subsets of these pathways.
Nevertheless, our data are consistent with the notion that the active fraction of branched Arg-rich peptide−PNAs does not use a different pathway of uptake compared to the linear R-Ahx-R peptides.
Some natural products have shown anti-staphylococcal activities weaker than others antibiotics, but synergic interactions may use different mechanism of action or pathways to demonstrate their antimicrobial effects, as resulting in the lowered MICs [ 40].
Pentacyclic triterpenoids have shown anti-staphylococcal activities and although individually weaker than common antibiotics produced from bacteria and fungi, synergistically these compounds may use different mechanism of action or pathways to exert their antimicrobial effects, as implicated in the lowered MICs.
The primary use of only one type of structural lipid may have been driven in part by the difficulties of reconciling metabolic pathways that use different chiral forms of the lipid glycerol backbone, with the mesophilic environment removing any intrinsic benefit of ether-linked lipids.
Both pathways employ Raf-1, yet use different modes of activation and different downstream effectors.
