Sentence examples for use as initial from inspiring English sources

We then merged the detected gene structures which have same exon exon junctions and constructed consensus sequences to use as initial gene models in the first step.

Methotrexate is considered the "anchor drug," and there is widespread acceptance for its use as initial therapy in most RA patients (category A) [ 9, 31, 32].

Dexmedetomidine use as initial sedation (2% versus 39%, P <0.0001) or at any point during the ICU stay (39% versus 82%, P <0.0001) significantly increased.

Although there is debate over which drug to use as initial therapy, it is generally accepted that the majority of patients will not be well controlled on one drug and will require multidrug therapy.

However, an important concern is the highly variable and unpredictable inter-individual PKs for cephalosporins and piperacillin and whether these drugs can be considered an appropriate agent to use as initial empirical therapy for critically ill patients with severe sepsis and septic shock, particularly in those with potentially less susceptible Gram-negative bacterial strains.

As there was no information available about the production rate of DA, the modification rate of ASYN and the degradation of DA, we decided to use as initial values the production and removal rates of Reactive Oxygen Species (ROS) and the rate of modification they induce on WT ASYN from [ 24] in order to obtain initial values for the rates of these reactions in realistic boundaries.

At first an initial 2-D image is reconstructed, then the final optimization parameters are used as initial values in the initiation of the 3-D reconstruction algorithm.

When using a local optimization algorithm, we used as initial seed the global maximum initially determined by means of simulated annealing.

The other trial, partly paid for by Roche, involved adding Avastin to the standard drugs used as initial therapy.

But the agency has never faced a situation like this, in which the larger studies, known as the intact trials, already showed that Iressa did not prolong lives when used as initial therapy.

Occasional patients with pituitary adenomas who have recurrences after surgery are treated with external-beam radiation; this is rarely used as initial treatment.