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After World War II, American firms probably led in the use and refinement of market research techniques, which spread throughout much of western Europe and Japan.
Nonetheless, we conclude that there is sufficient evidence to support the continued use and refinement of this procedure as a treatment for corneal stem cell deficiency.
The equations presented here represent some of the first allometric models for estimating grapevine C from berries to blocks, with the hope that widespread use and refinement of these techniques may lead to recognition and credit for the C storage potential of vineyards and other perennial woody crops, such as orchards.
Investigating subchondral bone changes and synovitis requires a critical use and refinement of these models.
In summary, in contrast to more traditional cancer therapies, the development, clinical use and refinement of imatinib and other targeted therapies could not have occurred without the considerable groundwork of biologists from many different disciplines.
The process of engagement itself had benefits in terms of connecting decision-makers with their peers and sparking increased interest in the use and refinement of priority setting frameworks.
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For his Ph.D., Franco has been researching the application of the "three R's" of animal experimentation -- ethical principles first proposed in 1959 that include, where possible, "replacement" of the use of animals, "reduction" in the numbers of animals used, and "refinement" of animal husbandry and experimental procedures so that they are less painful and distressful to the animals.
The study reported here was carried out in strict accordance with the recommendations in the standard operating procedures of the ILRI IACUC and adequate consideration of the 3R's (Replacement of animal with non-animal techniques, Reduction in the number of animals used, and Refinement of techniques and procedures that reduce pain and distress).
The Organizing for Quality framework is one of many that can be used to assess existing content and there is continued need for the use of and refinement of existing frameworks to evaluate QI initiatives.
This was anticipated and with increased use and experience, and refinement of the software interface, it is likely that the time and person burden will diminish.
In addition to surgical bone remodeling, several materials have been used for remodeling and refinement of the frontal bone.
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use and enhancement of
use and adjustment of
use and perfection of
use and improvements of
used and refinement of
use and placement of
use and burning of
use and promotion of
use and misuse of
use and production of
use and appearance of
use and disclosure of
use and quality of
use and enjoyment of
use and disposal of
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