The substantial animal use, low repeatability, and difficulty of in vivo examination limit its application.
Therefore, synthetic scaffolds represent potentially attractive alternatives to naturally derived substrates as they overcome many of the practical pitfalls associated with naturally derived substrates, including uncontrollable reproducibility, instability, poor mass transfer and difficulty-of-use.
Will complexity and difficulty of use kill the PC boom?
The reasons for returns: low battery life, touch-screen and difficulty of use.
For phase II, the Consortium redesigned the HTU to address its large size and difficulty of use.
These include insufficient availability to meet diagnostic needs, cost, accuracy of results in the presence of artefacts and difficulty of use in unsupervised conditions.
Assessment of study participation rates, time to completion, patient preferences, and difficulty of use revealed that PDA administration met or exceeded the practicability of regular paper administration.
However, to protect online transaction security, more security verification mechanisms are established which in turn increase the complexity and difficulty of using online services.
41 Careful management of RDT procurement, transportation, and storage can prevent RDT degradation and they can be an effective tool in malaria diagnosis, but good management of RDTs increases the cost and difficulty of using them in POC environments.
The method of choice depends on many factors: the level of resolution needed, the possibility to study neuronal circuitry or intact systems, the necessity to manipulate the experimental conditions, the interest in studying synaptic events or sensory responses and, no less important, the cost, time and difficulty of using the technique.
