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Here we use an experimental model of rat paw oedema formation to examine the effect of exogenously added histamine on the gene expression of H1R and bradykinin receptors B1R and B2R, alone or in combination to rupatadine, a second generation antihistamine agent.
Because mechanistic studies in humans are limited, a plausible way to address this question is to use an experimental model that simulates the clinically relevant UCB concentration exposure in the developing brain.
As discussed in [17], to accomplish this it is necessary to use an experimental model in which the transformation of a normal, immortalized cell by a single oncogene can be highly controlled, thus permitting the dissection of the sequence of events occuring after the initial alteration and the role of a particular gene or signal transduction pathway.
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Now, using an experimental model that required leaving the pristine conditions of the lab for the messier ones of life, a team of scientists from the Boston University School of Medicine have discovered what that allergen is.
Now, a team of scientists from the Boston University School of Medicine using an experimental model that required leaving the pristine conditions of the lab for the messier ones of life have discovered that the allergen usually is cockroaches.
In this study, we investigated the localization of tamoxifen in five ER-positive and five ER-negative breast tumor sections using an experimental model by MALDI-MSI.
In previous studies using an experimental model of taurocholate-induced acute pancreatitis in rats, we observed the generation and release to the bloodstream of specific halogenated lipids [9].
To investigate this, we used an experimental model of sepsis [13 15] inducing the systemic inflammatory response and neutrophil granulocyte activation, by administration of endotoxin.
This study used an experimental model of a constructed wetland to evaluate the risk of mercury methylation when the soil is amended with sulfate.
Therefore, we used an experimental model system (EMS) that was constructed to produce multiple micro-landscapes in which the habitat-loss and habitat-fragmentation impacts were potentially distinguishable.
Copland et al. [21] used an experimental model of acute ventilator-induced lung injury (VILI) to determine which genes changed their expression depending on inspiratory volumes, and they identified various genes with overexpression.
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