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For this 2D DTI scan, we use an echo planar imaging (EPI) readout with gradients (b = 1000 s/mm) applied in 25 directions [ 22, 23].
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Functional images covering the whole brain were acquired axially using an echo planar imaging sequence (TR = 2000 ms, TE = 40 ms, flip angle = 80°, matrix = 64×64, FOV = 24×24cm; 4mm thickness and 0.5 mm gap, 23 slices).
Functional scans used an echo planar imaging sequence (TR=3 s; TE=35 ms; flip angle=90; voxel size=1.8×1.8×4 mm; 112 volumes).
In both cases, functional MRI images were acquired using an echo planar T2*-weighted gradient echo sequence (echo time = 51 ms, repetition time = 3000 ms, flip angle= 83°).
19 Task‐related BOLD signal changes were mapped using an echo planar imaging sequence (TR = 1,850 milliseconds, TE = 26 milliseconds, flip angle = 75°).
In brief, MRI data were acquired on a 3.0 Tesla GE Signa HDxt scanner (General Electric, Milwaukee, WI, USA) and fMRI data were acquired using an echo planar imaging T2* blood oxygen level dependent (BOLD) pulse-sequence.
Diffusion weighted images were obtained using an echo planar imaging sequence with 3 directions and 6 b-values (100/200/400/600/800/1,000 ms), TE = 53.47 ms, TR = 3,000 ms, 6 averages, acquisition time 8 min 24 s.
Forty-four transaxial gradient-echo images (echo time = 30 ms, flip angle = 85°, slice thickness = 2.5 mm, slice gap = 0.5 mm, FOV = 192 mm, matrix = 64 × 64, voxel size = 3 × 3 × 3 mm) covering the whole cerebrum were acquired during all sessions at a repetition time of 2.5 s, using an echo planar sequence and a Philips Achieva (3T) MR scanner.
The resting-state fMRI scans were performed using an echo planar imaging (EPI) sequence with scan parameters of repetition time = 2000 ms, echo time = 30 ms, flip angle = 90°, matrix = 64 × 64, field of view = 220 mm × 220 mm, and each volume comprised 33 slices with slice thickness = 5 mm without slice gap.
Resting-state fMRI scans were performed using an echo planar imaging (EPI) sequence with the following parameters: repetition time = 2,000 ms, echo time = 30 ms, flip angle = 90°, matrix = 64 × 64, field of view = 220 × 220 mm, slice thickness = 3 mm, and slice gap = 1 mm.
Functional data were acquired using an echo planar imaging sequence with a 90% flip angle and using generalized autocalibrating partially parallel acquisition (GRAPPA) with an acceleration factor of 2 in 31 near-axial interleaved slices (in-plane resolution 2.1 × 2.1, slice thickness 4 mm; distance factor 10%; field of view 200 mm) with TR = 2,000 ms and TE = 30 ms.
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