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Here we use a variance component approach to look for dominant and imprinted QTL associated with bodyweight and conformation score measured at 40 days in a two-generation commercial broiler population.
Although the best test may depend on context, we note that Lin et al. used a different model than we did and, in particular, did not use a variance component approach.
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Using a variance component decomposition approach, the latter method allows flexibility in handling complex data sets.
Heritabilities for CVD risk factor phenotypes are estimated using a variance component approach.
The nine selected chromosome segments were first scanned for single QTL using a variance component approach.
This fits a mixture of normal distributions to the empirical data dynamically using a variance component model.
Therefore, to perform a genome-scan for QTL using a variance component based analysis, an IBD matrix is needed for each tested genome position τ.
QTL mapping using a variance component approach requires identity-by-descent (IBD) relationship matrices as variance-covariance matrices for testing QTL effects at each genetic position.
All transcripts associated with an estimated heritability higher than 0.05 (1,057 transcripts) where then subjected to QTL analyse using a variance component approach [ 61].
As SardiNIA project is a family based study, to test for association while accounting for relatedness, we used a variance component method implemented in Merlin.
For a family-based sample, the phenotypic variance-covariance matrix can be parameterized to include the variance of a polygenic effect that has then been estimated using a variance component analysis.
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