Sentence examples for use a recessive model from inspiring English sources
To test if individuals with the 148M mutations had lower RBP4 protein we chose to use a recessive model.
The main rationale for this was that the previously published Mendelian Randomization study [12] to examine this association used a recessive model and we wished to pool results from that study with those from our new studies.
Some differences were observed in girls using a recessive model.
In DRD2 gene, using a recessive model, we demonstrated that rs1079727 was significantly associated with dyslexia with the allele C as a risk factor after Bonferonni correction.
It might be possible, in principle, to devise some kind of alternative weighting scheme aimed specifically to detect associations using a recessive model.
An additional 4 SNPs reached Bonferroni corrected statistical significance using a dominant model for the top-strand allele, and two SNPs reached Bonferroni corrected statistically significance using a recessive model for the top-strand allele (Table 2).
These data were best fit using a recessive model (TT genotype compared to TG plus GG genotypes), which was therefore used as the statistical analytic model throughout the study.
Based on the previous findings [ 10, 36], we only considered an additive model in testing the associations between these SNPs and adiposity phenotypes except for the SNP near INSIG2 for which we used a recessive model [ 5].
They obtained a maximum two point lod score of 4.5 at marker D17S1289 (θ=0.07) and a three point lod score of 4.3 using the markers D17S1289 and D17S921 (θ=0.10) using a recessive model.
A sensitivity analysis using a recessive model and restricting to individuals with low BMI did not alter this and the OR increased to 1.34 (95% CI 0.96 1.86), but did not reach significance (p = 0.08).
No significant increased risk of MetS was observed overall for AA homozygotes, for either the IDF or NCEP ATP III definitions, upon repeating the analyses using a recessive model for the FTO rs9939609 A allele.
