Another more recent example of a vaccine failure using a single S. aureus antigen is Merck's monovalent vaccine based on IsdB, a conserved iron-scavenging protein expressed on the surface of S. aureus which was identified using a novel screen for antigens which are highly expressed during infection.
In work published 15 March 2004 in Cancer Research, the Burnham team used a novel proteomics screen based on probes that bind to the active site of the enzyme target.
In this closeup, Canales and Walz discuss how CNV are associated with normal variation, genomic disorders, genome evolution, adaptive traits and how the use of a novel screen described by Ermakova et al in this issue that is designed to identify human disease-relevant phenotypes associated with CNV in the mouse can help elucidating susceptibility or predisposition to diseases loci.
In this study, we used a novel, integrative epigenetic screening approach to specifically look for coordinately expressed genes in human NSCLC whose transcription is driven by promoter demethylation.
In this study, we used a novel, integrative epigenetic screening approach combining 5-aza-deoxycytidine and trichostatin A (5-aza/TSA) treatment of normal lung cells and mRNA microarray expression analysis of primary tissue to identify genes that are both activated by DNA hypomethylation and differentially upregulated in a coordinated fashion in NSCLC.
By using a novel method of screening, approximately 16,000 compounds were evaluated for their ability to eradicate breast CSCs.
In this article the prevalence of potential drug interactions in outpatient day-care patients treated with anti-cancer agents is studied using a novel more extensive screening method.
To overcome these limitations, Li and colleagues used a novel multiple survival screening (MSS) algorithm, designed to extract the most robust signals from the data [ 11].
In this study the prevalence of potential drug interactions in outpatient day-care patients treated with anti-cancer agents will be investigated using a novel more extensive screening method.
The aim of the present study is to gain more insight into the prevalence of interactions and duplicate prescriptions among patients being treated in the outpatient day care departments for oncology and hemato-oncology using a novel more extensive screening method.
