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If clinicians use a high threshold (>42%), the weight of overtreatment would be higher than missing high-risk disease.
The method was adopted to purposely use a high threshold of 650 mg/cm so all possible trabecular bone was detected.
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In particular, we use a higher threshold in the prediction of unique l-mers.
Furthermore, if no technical replicates were available, the authors of NOISeq recommended to use a higher threshold such as q = 0.9.
However, because of concerns that this test and/or threshold might delay weaning [ 7, 8], some groups use a higher threshold, such as 125 breaths per litre per minute [ 5], or omit RSBI altogether [ 1, 4].
We use a higher threshold due to the fact that GO terms naturally contain more noise since they were inferred from sequences that do not neccessarily have to be orthologues, or even homologues.
However, since there were only eight GRN mutation carriers in our FTLD population, further carriers will need to be assessed to more definitively decide on the optimal cut-off; in the meantime it may be prudent to use a higher threshold than 112 ng/ml to be more certain of a high sensitivity, without materially lowering specificity.
This method requires I Δ (x, y) to be segmented twice, first using a high threshold value τ S and second using a low threshold value τ T. Equation 9 is used to compute τ S and τ T using scaling factors α S and α T, respectively.
We thus detected this strategy using a high threshold for surface coverage.
When using a high threshold (0.09 in this example) for the movie images, the larvae tracks are broken due to lack of sensitivity (Figure 3a).
The peaks were detected on the shot noise process
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