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Herein, we use a functional assay to investigate how downstream tissues interpret region-specific outputs by using in vivo exposure to long day photoperiods to temporally dissociate the SCN.
In future work it would therefore be beneficial to use a functional assay on the neuronal cells differentiated on the platform and compare the results to cells differentiated manually.
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Fig. 2 Quantitative MUC assay for six fosmid clones that were identified using a functional assay with the CMB substrate.
The new compounds were tested as correctors and potentiators in CFBE41o-expressing F508del-CFTR using a functional assay.
We examined the genomic interval containing human ACAN for transcriptional enhancers directing expression to cartilage, using a functional assay in transgenic zebrafish.
These isolates were also analyzed for oseltamivir resistance using a functional assay.
To confirm this role, we used a functional assay extensively used to study EB2 mRNA export activity.
We also used a functional assay to show that the PY motif of SGK is essential for preventing Nedd4-2 inhibitiof of ENaC by SGK.
We identified DMEs using a functional assay and found that the sequence characteristics of DMEs are distinct from CGIs and from the bulk of genomic CpG dinucleotides.
The data reported in Figure 3D were obtained using a functional assay that assessed levels of active protein in the culture media of stimulated cells (see Materials and Methods).
These studies require proof of capacity using a functional assay, usually tumor growth in xenograft transplants.
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