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We did not use a continuous glucose monitoring system (CGMS) in our study.
This study reports the results of data analysis from a subset of patients who volunteered to use a continuous glucose monitoring system (CGMS) to assess glucose variability.
RESEARCH DESIGN AND METHODS Continuous glucose monitoring data were collected from a subset of patients (n = 90) who agreed to use a continuous glucose monitoring system during an active-controlled, randomized, open-label study evaluating the safety and efficacy of insulin glargine and NPH/Lente insulin used with insulin lispro as part of an MDI regimen.
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Interstitial glucose was recorded for 20 h after leaving the laboratory using a continuous glucose monitoring system.
Daily glucose levels were recorded by the diabetes group using a continuous glucose monitoring (CGM) system (MiniMed Paradigm Real Time, Medtronic Inc).
A subset of patients (CNL, n = 46; EXP, n = 47) used a continuous glucose monitoring (CGM) device (Dexcom Seven Plus; Dexcom, San Diego, CA).
They were evaluated using a continuous glucose monitoring system over 72 h in the follicular (4th 8th days) and in the luteal phase (18th 22nd days).
In addition to conventional glucose indicators, blood glucose variability in a stable state was determined by calculating the mean amplitude of glycemic excursions (MAGE) using a continuous glucose monitoring system.
Of note, Dungan et al. (1) used a continuous glucose monitoring system to measure the area under the curve for glucose levels exceeding 180 mg/dl, while the present study was based on self-measured glucose values.
One study additionally assessed glucose variability in a subgroup using a continuous glucose monitoring system, 52 and this again showed reduced variability with insulin detemir compared with NPH insulin.
Participants with type 1 diabetes were assessed for HbA1c history and lifetime adverse events, and glucose levels were monitored using a continuous glucose monitor (CGM) device and standardized measures of cognition.
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