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Our study findings suggest that the FDA did not use a consistent approach to address surrogate outcomes when reviewing the drug approvals included in this study.
Our results suggest that the FDA did not use a consistent approach to address surrogates in assessing the benefits and harms of drugs for COPD, type 1 or 2 diabetes, glaucoma and osteoporosis.
Our survey findings suggest that, for three of the diseases examined (COPD, diabetes and glaucoma), drugs are approved based on their treatment effects on surrogate outcomes, but that the FDA does not use a consistent approach for surrogates in order to evaluate these drug applications.
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The Housing Ombudsman Service deals with thousands of disputes each year and our experience shows the best results are achieved when landlords deal directly with issues using a consistent approach.Here are three key ways to improve how you handle housing complaints: Be fair Give everyone involved the chance to explain his or her point of view, and respect privacy and confidentiality at all times.
Boundedness can be guaranteed by using a consistent approach with respect to the constraints imposed on the transport variables, such as dispersed phase volume fraction.
Thus the decking can be designed using a consistent approach through the whole construction process, ignoring any increase in strength due to the stabilizing effect of wet concrete.
This study design has the benefit of prospective data collection using a consistent approach.
Our study is also unique in that two allergy/asthma outcomes were analyzed using a consistent approach.
The aim of our study was to assess the joint effects of the four established susceptibility loci HLA, INS, CTLA4 and PTPN22 in type 1 diabetes, using a consistent approach with both population-based case-control and family trio designs and with large sample sizes.
The purpose of this study was to reevaluate immunoglobulin levels collected over several investigations by using a consistent approach to data analysis to determine whether individuals who live near several Superfund sites are more likely to have test results below or above the reference range than individuals who live in comparison areas with no Superfund site.
The model was generated with the McCad conversion tool from available CAD models using a consistent integral approach.
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