Sentence examples for use a conditional knockout from inspiring English sources

In this study, we use a conditional knockout strategy to establish a requirement for Cited2 in adult HSCs.

1) It would be helpful to know why the authors had to use a conditional knockout for epsin 1.

Please improve and show epsin clearly. 1) It would be helpful to know why the authors had to use a conditional knockout for epsin 1.

In the present study, we use a conditional knockout system to specifically delete Ngn3 from the ventral forebrain, resulting in a depletion of Pomc expression in ARC neurons, a decrease in leptin sensitivity in the ARC and VMH nuclei, and an associated obesity due to hyperphagia and reduced energy expenditure.

On-going studies using a conditional knockout mouse model for Dhs will help us to more clearly differentiate the impacts of DOHH and DHS function in higher eukaryotes.

To test this hypothesis, we used a conditional knockout approach to eliminate E-cadherin specifically in the intestinal epithelium during embryonic development.

Herein, we sought to specifically address the role of Cbfβ in cartilage and bone development by using a conditional knockout (CKO) approach.

Here, we examined T cell and thymic epithelial cell development using a conditional knockout approach.

Using a conditional knockout (KO) mouse model for Cobra1, we demonstrate a critical role of Cobra1 in early embryonic development.

The most appropriate approach to avoid this kind of bias would be using a conditional knockout model.

The requirement of NBS1 for efficient CSR has also been demonstrated by analyzing NBS1-deficient mouse B cells using a conditional knockout strategy [29], [30].