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The study results are also limited by the lack of information about the participants' drug usage throughout the study period.
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Our findings further suggest that usage declined throughout the study period.
There was varied and sporadic usage of rescue medications throughout the study without any clear trends or safety concerns identified.
We additionally evaluated how well short measures of usage predicted the study average during stable periods of usage.
All studies saw a decrease in programme usage throughout the intervention period and 12 studies had attrition rates of greater than 20%.
As an example, Lautenbach et al. [ 35] report that after the fourth year of vancomycin reduction efforts, vancomycin usage had increased to baseline, while VRE acquisition continued to increase throughout the study period.
Paracetamol was provided as rescue medication throughout the study at a daily dose of up to 4000 mg, and the usage was recorded.
All studies showed a decrease in programme usage throughout the intervention period.
The effect continued throughout the study, the drug agency said.
Benzodiazepines allowed throughout the study.
Complete confidentiality was ensured throughout the study.
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