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Despite this important advancement in the usage of whole tissue microscopy as a primary skin penetration evaluation technique, the authors did not address their ultimate sensitivity.
Today's state of the art in high-throughput sequencing already allows the usage of whole genome sequencing for research projects and of whole exome sequencing for daily clinical routine.
Ideally, usage of whole blood is preferred but the techniques that are now available are often not sensitive enough, clinically, as has been shown by others investigating a commercial real-time PCR test currently available [ 17– 17].
The impedance aggregometry provides several advantages compared to LTA, for example, the usage of whole blood samples preserving the natural environment of the platelets and the elimination of the time-consuming centrifugation step, thus avoiding the collection of large blood volumes and the loss of large platelets.
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Although there is uncertainty about the diagnostic sensitivity of these methods, we showed that simultaneous usage of a whole battery of techniques might improve their sensitivity in the detection of CS.
An advantage of this method is the usage of the whole array of experimental data, including high temperature part of the thermogram, which is especially important at determination of the order n, determination of the reaction mechanism, and model fairness.
In other words, it is necessary to find out how much energy is required to support a specific FER value, and how to effectively regulate the power usage of the whole sensor nodes.
Additionally, the results confirm the importance of both the filtration process of the local directional wave climate and the usage of the whole directional spectra in stability studies and coastal engineering practice.
On the main chromosome there are 11 genomic islands (GI) that display an unusual SCU, when compared to codon usage of the whole chromosome (Figure 6).
The shape of the curve qualitatively reflects the coreceptor usage of the whole population within the relevant isolate.
The behavior of pooled-α+β PCGs in different species varied with respect to the usage of the whole set (62) of codons encoding amino acids.
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