Exact(1)
Considering that the strength of evidence derives not only from the quality of the study design, but also from usage of validated outcome measures, we combined the information provided by these two recent reviews and assessed the appropriateness of the rating instruments used in clinical trials on BoNT treatment in focal dystonia.
Similar(59)
The use of validated outcome measures should be encouraged.
Validated outcome measures - This review has emphasised the applicability of validated outcome measures.
Although the incidence of celiac disease (CD) is increasing, studies have been hampered by the lack of validated outcome measures.
Bench-to-bedside plans for fragile X syndrome are severely limited by the lack of validated outcome measures.
Therefore, the development of validated outcome measures in these autoimmune dermatoses is critical.
Other solutions include the usage of validated and standardized questionnaires (e.g., NASA-TLX [43]) or the measurement of drivers' eye glance behavior [44].
Although the consistent use of validated measures assessing disease severity and QoL in AD was not observed 20 years ago, this study found a promising trend of increased usage of validated instruments in clinical trials that measure AD disease severity and QoL in the past decade.
Monitoring response to therapy becomes subjective and unreliable in the absence of such validated outcome measures.
We will use below described validated outcome parameters, which will be assessed by means of questionnaires.
Therefore, as no validated objective outcome measures for patellofemoral pain syndrome are currently available, the use of validated subjective outcome measures seems appropriate.
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