Before 2005, more than half of the researches have used non-public datasets; however after that, with the help of PROMISE repository, the usage of public datasets reached to half [8], because the results are more reliable and not specific to a particular company.
Usage of various datasets and phylogenetic methods can result in different positions of the Saaremaa strains [ 74].
The usage of control datasets allowed us to substantiate the choice and also to estimate the fraction of false positives among the cohort of underrepresented sites.
The usage of different datasets improves the generalizability of results, as radically different methods are used to delineate functional areas in STN (diffusion-weighted imaging) and in the rest of the basal ganglia (covariance of relaxometry-based multiparameter maps).
Further, the need to negotiate access to datasets generated via proprietary, digital platforms distinguishes DE from usage of such public datasets in traditional epidemiology.
In order to normalize codon usage within datasets of differing amino acid compositions, relative synonymous codon usage (RSCU) values were calculated.
Identification of a miRNA target by usage of gene and miRNA datasets taken from two relatively divergent tissues (such as the embryonic and the adult liver) is relatively complex since, as mentioned above, the mRNAs are most likely regulated by additional machineries.
In order to justify usage of even smaller genotyping datasets, we calculated the expected bias from supplementing the reference set with admixture components of populations genotyped over fewer markers down to randomly selected 500 markers.
The growth of grid computing gives a reliable environment for the effective usage of this distributed huge dataset.
BPP/HPL ratios among accepted miRNAs have a smaller inter quartile range but larger values, which translates to more bonds within their hairpins for human, but interestingly not for rodent models, possibly due to the usage of a mixture rodent dataset for training.
