These results could be attributed to fewer hypercalcemic patients, and low usage of calcium-containing phosphate binders, in our cohort.
The following covariates were incorporated into the analysis with a stepwise procedure; duration of diabetes, smoking status, triglycerides, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, HbA1c, eGFR, log CRP and the usage of insulin, calcium channel blockers (CCB), angiotensin receptor blockers (ARB), statins and anti-platelet agents.
The purpose of this study was to scale-up the usage of strontium-doped calcium polyphosphate (SCPP) to major load-bearing applications in bone substitute application.
These advocate broad usage of expensive non-calcium-based phosphate binders such as sevelamer.
In contrast, ascertainment of calcium supplement usage may have less error, thus making it easier to detect an association with calcium supplement use, as we found in this study.
Release of calcium from the sarcoplasmic reticulum of muscle cells has been shown to be increased with antipsychotic usage [ 15] and it may be that this could lead to the rigidity, muscle breakdown and hyperthermia seen in NMS.
To improve the validity of our exposure estimate, we used a calibrated calcium intake obtained by usage of linear regression coefficients between food records (FR) and the food frequency questionnaire (FFQ): (R i FR=αFR+ βFR* FFQ i, (R reported calcium in the food records, i in the individual)).
The two main kinds of calcium supplements are calcium carbonate and calcium citrate, which are distinguished by the compound that is used to combine with the calcium.
It's called 'milk of calcium.' That's another kind of calcium that's always benign".
