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Usage of aspirin and antiplatelet drugs did not differ between treatment arms at discharge (97.6%), 30 days (87.6%), or 12 months (51.5%).
Our findings, which are particularly relevant to Chinese, may also explain the relatively low usage of aspirin in Asians than Caucasians [ 8].
Over-the-counter usage of aspirin in cases and controls must be considered as our inability to capture such use may have also contributed to the null findings.
Of the 6,454 patients (mean follow-up: median [IQR]: 4.7 [4.4] years), usage of aspirin was 18% (n = 1,034) in the primary prevention cohort (n = 5731) and 81% (n = 585) in the secondary prevention cohort (n = 723).
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(DOCX 118 KB) 10194_2013_599_MOESM2_ESM.tiff Additional file 2: Figure S1: Medication usage between the two groups demonstrates no significant changes apart from the use of aspirin.
Complicating the use of aspirin for prevention is the phenomenon of aspirin resistance.
Pre-treatment pain intensity influenced usage pattern of Aspirin in the self-medication of headache and other pain states.
Over-the-counter usage of low-dose aspirin is possible but previous investigation within the General Practice Research Database found that the majority of chronic aspirin use was captured by prescription records [ 36].
In our cohort, usage of low-dose aspirin was associated with a 2.2-fold increased risk of upper GI bleeding.
Exclusion criteria were: rest pain, Buerger's disease, ischemic tissue necrosis, surgical or endovascular procedures within the past 3 months, unstable coronary artery disease, symptomatic cardiac arrhythmias, recent (<3 months) DVT, conditions that limited exercise capacity other than IC; and usage of >81 mg/day of aspirin or 1200 mg/day ibuprofen.
The percentage of aspirin usage was 18% (n = 1034) and 81% (n = 585) in the secondary prevention cohort.
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