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Because BRCA1 and BRCA2 are involved in homologous recombination (HR -based DSB repair, tHR -basedeDSBrepaircy of microhomology-mediathe indelevatedRCA1 or BRCA2 mutant cancers presumably refrequencyage of alternative methods of DSB repair in these cancers.
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The report says increased usage of alternative advice services will cost other departments £53m a year.
The two main sources of heterogeneity in BORIS mRNAs were the usage of alternative promoters and splice sites.
However, due to usage of alternative splicing and/or of alternative polyadenylation sites, 3'-UTRs sometimes differed in sequence.
The 3′ regions of NFAT genes are also diverse due to alternative splicing and usage of alternative 3′ exons.
This pattern is consistent with usage of alternative boundaries in JEC21 (supported by cDNA evidence for usage of alternative boundaries in 4 cases), and with usage of only a single boundary in some relatives.
The E2f3 gene encodes two protein products, E2F3a and E2F3b, through the usage of alternative promoters.
The usage of alternative promoters greatly multiplies the transcriptional complexity available within the human genome.
The sTIN subtype separated the samples by the preferred usage of alternative exon skipping or inclusion.
The usage of alternative translation start sites is quite possible (some examples were demonstrated experimentally).
There are several alternative transcripts for the NFAT genes, which are generated by usage of alternative 5′ and 3′ exons and alternative splicing.
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