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Nonetheless, the observations on urinary conservation of Si and changes to bone/body length, growth plate and bone-phosphorus concentrations are significant, novel and deserve further study.
These results suggest that rats actively maintain body silicon levels via urinary conservation, but the low circulating serum silicon levels during silicon deficiency result in inhibition of growth plate closure and increased longitudinal growth.
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This suggests that, in states of Si deprivation, urinary Si conservation, perhaps through renal reabsorption, can occur.
However, evidence for urinary silicon conservation (to maintain tissue levels), changes in bone/body lengths, bone calcium:phosphorus ratio and differences at the growth plate with silicon deprivation are all novel and deserve further study.
One or more AQPs may be differentially expressed in the kidneys of the Si-deprived group, suggesting potential Si transport (i.e. the reabsorption of Si from urine), explaining our finding of urinary Si conservation in this group.
The following experiments were aimed at 1) finding if old mice have a deficit in water conservation, 2) if so, whether it occurs prematurely in Ku86-/-mice, and 3) whether any deficit involves defective urinary concentrating ability.
And urinary tract infections.
Conservation Dept.
Energy conservation.
Current conservation status: Thriving.
The Conservation Dept.
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