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The defendants, who have been detained for a week, will face "an urgent trial before the criminal court", he said, but no date has been given..
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There are almost no data regarding the treatment of patients with HER-2-positive ABC who relapse on or shortly after adjuvant trastuzumab and urgent trials are needed for this poor prognosis population.
Over half the sample (n = 27/45, 60%) of practitioners had experience of using deferred consent in an emergency or urgent care trial.
Data were collected on 13 emergency and urgent care trials conducted since 2004.
Informed prospective assent was sought from children in four trials, all were urgent elective care trials (<16 years).
Stroke experts are sharply split about the device's value — which is why, regardless of their view, they agree it is urgent for such trials to be conducted, to prove or disprove the benefit to stroke patients.
There is also an urgent need for trials to evaluate clinical outcomes among these populations in Europe.
The 2009 and 2010 roundtables noted the urgent need for trials that related nutrient biomarker data to clinical outcomes to identify cutoffs of nutrient adequacy that minimize misclassification errors (2– 4).
4 A recent Cochrane review stated that iron treatment may improve developmental outcomes in young children with IDA, but the existing evidence is scarce and there is an urgent need for trials assessing long-term effect of this therapy.
A call for an urgent need for trials focusing on RRT indications and timing is also the conclusion of the study by Clec'h and coworkers; manipulating data from the French longitudinal prospective multicenter Outcomerea database in a propensity analysis (2,846 critically ill patients), a comparison between critically ill patients treated with RRT and those not treated with RRT was conducted [ 35].
Researchers working on the crisis wrote the outbreak was "clearly not the ideal situation for doing a vaccine trial," but urgent international need for a solution helped spur work with local government to establish an effective method "in compliance with good clinical practice and international standards".
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