Although these authors propose a prediction rule to select the patients with PN who could benefit from an ultrasound study, we believe that, given the high morbidity and high prevalence of alterations requiring urgent instrumentation, an ultrasonographic study should be performed in all cPN patients.
This explains the urgent necessity to identify the molecular alterations in pancreatic carcinomas in order to develop new treatment strategies for this neoplasm.
Thus, there is an urgent need to elucidate the genomic alterations and molecular events associated with the various ESCC stages to enhance our understanding of these tumors, aid in early diagnosis, identify therapeutic targets and develop prevention strategies.
However, there is an urgent need for a non-invasive and accurate test to diagnose early alterations in the lipid metabolism leading to fatty liver disease.
Enough and our partners in the Sudan Now campaign believe that significant alterations in the emerging U.S. approach to Sudan are necessary and urgent.
Climatic change, increasing prevalence of droughts, alterations to groundwater availability and flooding periodicities make such work increasingly urgent since freshwater floodplain forests are a vital human resource that is under threat.
The reasoning to include this factor is that the percentage of urgent patients differs substantially between the different patient groups and subsequently, an alteration in the number of patients per patient group is likely to change the overall percentage of urgent patients.
Some adverse events, however, interfered excessively with daily life, such as stomatitis and taste alteration requiring changes in food habits, hand foot syndrome limiting walking and the urgent pattern of diarrhoea with risk for soiling.
The importance of the impact of histopathological factors on prognosis and an awareness of the role of morphologic alterations in ensuring an accurate pathologic assessment [ 16, 26, 27] indicate the urgent need for a new, label-free, real-time, noninvasive technique for differentiating among the various morphologic alterations induced by radiochemotherapy.
There is an urgent need for physiologically relevant ex vivo culture systems based on primary breast cells in which the significance of identified alterations can be tested.
This alteration allows semi-urgent GE and Colonoscopy procedures and Oesdil procedures to be pooled.
