Exact(1)
This may have been due to the peculiarity of the groups enrolled (e.g. mostly pregnant women in Moscow and mostly children in St . Petersburg, poor uptake, the ability of the vaccine to prevent hospitalization, or a combination of these factors, although these influences remain to be assessed over the coming years.
Similar(59)
The cytotoxicity of EILDV-conjugated micelles was observed close to 1.5-fold higher than plain ETO after 72 h of drug incubation, demonstrating controlled release of drug inside the cell after enhanced intracellular uptake with the ability to selectively target cancer cells.
The positive correlation of gp78/AMFR and pAkt expression in an invasive breast cancer tumor cohort, the PI3K sensitivity of AMF/PGI uptake and the ability of AMF/PGI to stimulate PI3K-dependent cell survival suggests that PI3K is such an effector [30], [41].
The problem of relying solely on in vitro data to predict photosensitiser efficacy was demonstrated by examining the uptake and the ability to mediate photocytotoxicity of mono-, di-, tri- and tetra-sulphonated species of chloroaluminium phthalocyanine (AlS1-4Pc) in monolayer cultures of murine Colo 26 cells and in both monolayer and spheroid cultures of human WiDr cells.
According to the biphasic model, a S611D construct should shut down the uptake ability of the transporter while the DD construct should demonstrate a reduced or eliminated 5HT uptake capacity due to its intracellular localization.
The fatty acid uptake assays demonstrated the ability of Arabidopsis AAE15 to activate exogenously added fatty acids of different carbon chain length.
In addition, insulin-mediated uptake must have the ability to capture inter- and intra-patient variability in the time-varying insulin resistance observed in these patients.
In soil, a large proportion of the total P pool is not directly available for plant uptake [23], and the ability to solubilise phosphates in the rhizosphere has been viewed as an important function of PGPM [24].
It is important to note that while the 15-minute uptake assay determines the ability of cells to internalize RBV, the long-term accumulation is dependent on the cellular metabolism of RBV.
For example, the repression of Tlr4, SOCS1 and SOCS3 expression by SRA may contribute to the SRA-induced increase in insulin-stimulated glucose uptake, as might the ability of SRA to induce the expression of Sorbs1.
Overall, the coordinate effects of Rab25 mutation on AKT binding and ATP levels, glycogen content and glucose uptake suggests that the ability of Rab25 to bind and regulate AKT plays a critical role in the ability of Rab25 to regulate cellular bioenergetics, a contention supported by the PI3K, AKT and GSK3 inhibitor studies.
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