This uptake pattern is shown on Fig. 2b.
The colic uptake pattern always disappeared after sorafenib withdrawal.
Figure 3 Uptake pattern in one patient of Group 1. Uptake pattern in one patient of Group 1 before (A), during (B, C) and after(D) sorafenib treatment.
The polar map patterns include (1) a diffuse uptake pattern and (2) a basal ring-like and/or lateral uptake pattern.
Eyes show a distinct uptake pattern in B16F1 tumor bearing mice (right panel).
Further preclinical and clinical studies are needed to better understand the mechanisms of this uptake pattern.
The focal on diffuse cardiac 18F-FDG uptake pattern could thus safely be considered physiological.
Tracer uptake pattern was considered patchy in case of distinct spots with high uptake in muscles.
Healthy subjects of the HEP group revealed diffuse uptake pattern in 31% (5/16) and basal ring-like and/or lateral uptake pattern in 69% (11/16, Table 2), whereas those of the LF group did diffuse uptake pattern in 29% (2/7) and basal ring-like and/or lateral uptake pattern in 71% (5/7, Table 3).
This uptake pattern appeared rapidly (one month) and disappeared after sorafenib withdrawal.
The paradigm for determining a dynamic [18F]FDG uptake pattern was demonstrated for future new therapeutic drug experimental use.
