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However, differences in biophysical properties such as lipophilicity, basicity, or passive permeation may also influence the apparent uptake of these compounds.
Also, the regional brain uptake of these compounds reached equilibrium with an 11C imaging time window.
The uptake of these compounds could involve a cellular uptake mechanism, such as mycobacterial porins that the inactive zwitterionic compounds 10 and 12 are not substrates for.
Uptake of these compounds appears to be multifactorial.
However, uptake of these compounds into the brain is less than into other organs.
In contrast, there was a better correlation between the redox potential and uptake of these compounds.
Similar(41)
In this work, the development of a further Quantitative Nanostructure Activity Relationship (QNAR) model was performed by linear multiple linear regression (MLR) and nonlinear artificial neural network (ANN) techniques to accurately predict the cellular uptake values of these compounds by dividing them into three groups.
The aim of this study was to determine whether irreversible TKIs have improved tumor-targeting properties and kinetics and to investigate the influence of drug efflux transporters on the tumor uptake kinetics of these compounds.
Similarly, the uptake of these three compounds in non-melanoma tumor was low.
Under these conditions, aha2 knockdowns show enhanced root growth compared to wild-type plants because of the reduced proton motive force that energizes the reduced uptake of these toxic compounds.
Plants exposed to oVOCs increased their normal uptake of the compounds, absorbing 40% more than expected.
More suggestions(15)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com