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This decreased tumour viability in the core of the tumours is in close accordance with [18F]FDG findings, which generally displayed higher uptake in the outer tumour areas.
There is increased FDG uptake in the outer rims of the tumor and reduced uptake in the center of the tumor (probably due to necrosis).
The 89Zr-bevacizumab image on day 4 also shows high uptake in the outer rims of the tumor (T1) and high blood activity concentration (aorta descendens (AD) and heart chambers (H)).
The 89Zr-bevacizumab image on day 7 shows high uptake in the outer rims of the tumor but low uptake in healthy tissues as well as low blood activity concentrations.
However, this zone of demineralizing front was significantly more extended in the elevated fluoride group D2 representing mainly inhibition of demineralization in the inner part of the lesion in contrast to mineral uptake in the outer part of the human enamel lesion.
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The iron uptake machinery encoded by different A. baumannii strains may differ, as variation in the composition of siderophore mediated iron uptake proteins in the outer-membrane has been shown in a study on different Acinetobacter strains [ 20].
Coronal slices of the PET imaging clearly showed a heterogeneous uptake of [18 F]12 in the outer rim of KB xenografts.
The omp Gal -lacZ-galTK-galPII -galE operon in two S. baltica strains (OS185 and OS223) encodes an additional novel transporter from TBDT family, named OmpGal, which is likely involved in lactose uptake through the outer membrane.
In the ovary, cholesterol uptake from the outer mitochondrial membrane to the inner mitochondrial membrane is the rate limiting step.
[18F]FPyKYNE-losartan is a novel PET imaging agent displaying high tissue uptake in the kidney cortex and outer medulla and binding selectivity for AT1R over AT2R [21].
While the uptake of nitrate into the root symplast depends on the concentration in the outer medium, the xylem loading process depends mainly on the shoot demand and the content of reduced N-compounds in the phloem [ 31].
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