Comprising about 40 50% of body mass, skeletal muscle is the chief peripheral insulin responsive tissue, responsible for glucose and fatty acid uptake in response to insulin.
LOAD fibroblasts demonstrated a shift in energy production to glycolysis, despite an inability to increase glucose uptake in response to IGF-1.
Heightened glycolysis in combination with a decreased mitochondrial metabolic potential and a defective redox potential in LOAD fibroblasts appears to be disease- and not age-specific features, while the inability to increase glucose uptake in response to IGF-1 signaling is a characteristic of both healthy old and LOAD cells.
This study assessed the effects of plastic film mulch and P fertilization on alfalfa forage yield and shoot P uptake in response to improved soil moisture and soil P availability in a dryland farming system of northwest China.
Human brown adipose tissue (BAT) presence, metabolic activity, and estimated mass are typically measured by imaging [18F]fluorodeoxyglucose (FDG) uptake in response to cold exposure in regions of the body expected to contain BAT, using positron emission tomography combined with X-ray computed tomography (FDG-PET/CT).
Plants have evolved mechanisms to increase Fe uptake in response to conditions of limited Fe bioavailability.
Both radiotracers demonstrate a dose-dependent increase of tracer uptake in response to LPS stimulation (logarithmic scale).
Figure 1 Changes in land carbon uptake in response to increasing nitrogen deposition and both nitrogen deposition and forest regrowth.
A three-dimensional region of interest analysis was performed to determine the percent change of 18F-FDG uptake in response to treatment.
Previous studies in NSCLC patients also showed an early (2 14 days) reduction of 18F-FDG uptake in response to treatment with EGFR TKIs [11 14] that was predictive of morphovolumetric tumor response, PFS, and OS.
Insulin resistance (IR) is defined as the inability of target tissues to increase glucose uptake in response to insulin, which eventually leads to type II diabetes mellitus (T2DM) (Eckel et al. 2005; Samuel and Shulman 2012).
