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As detected by propidium iodide (PI) uptake, exposure to I-BET762 resulted in loss of plasma membrane integrity with a dose- and time-dependent effect (Supplementary Figure S1).
Similar(59)
Figure6 showed the MTT results demonstrated a concentration dependent uptake after exposure to Lf nanoliposomes.
Figure 6 showed that the MTT results demonstrated a concentration-dependent uptake after exposure to EGCG nanoliposomes.
We also evaluated fate and transport pathways of the ENPs in the experiments to elucidate routes of uptake and exposure.
Kinuya et al. reported on an increase in [99mTc]HL91 uptake after exposure to X-ray radiation [ 127].
This estimate was based on assuming 100% uptake, and exposure to a total of 10 biennial screens between the ages of 50 and 70 years.
No evidence of a cyanidelike effect was observed, in contrast to a severe depression of oxygen uptake following exposure to hydrogen cyanide.
There are physiological limitations with such cellular systems such as uptake, antimicrobial exposure (gentamycin), and cellular replication that may hinder experimental reproducibility.
To determine the time course of ethidium uptake after exposure of ATP, SCs in 24-well plates were placed on the stage of a spinning disk confocal microscope (Andor Technology plc, Belfast, UK) fitted with an environmental chamber (maintained at 37 °C).
Initial ITT analyses involving all those randomised, regardless of allocated group or whether they completed a Baseline Survey (BS) and received an FOBT, indicated no benefit on screening uptake from exposure to information about the importance of bowel cancer screening.
ImageJ was used to quantify the ethidium uptake after exposure to ATP, and integrated densities of ethidium fluorescence in 10 randomly chosen cells in each captured image were measured and averaged.
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