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The mechanisms of uptake and elimination of different metals in H. azteca are described [44 47].
Drug transporters mediate the uptake and elimination of drugs in various organs; therefore, having knowledge of how a transporter functions in the body would play a key role in ensuring drug efficacy in in vivo systems.
In order to investigate the latter two possibilities, we quantified uptake and elimination of AuNPs.
Drug transporters that mediate the uptake and elimination of statins have recently gained interest.
Differences in genes encoding potential Hg-transporters may affect uptake and elimination of Hg.
These values were chosen to determine the uptake and elimination of AuNPs at the EC50 dose of each AuNP tested.
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In addition, it is important to link the timing, duration, and route of exposure as well as the kinetics of uptake and elimination for a given set of chemicals to the biomarker of exposure.
Notwithstanding all of the new developments made and information gathered, it is surprising that very little is known about the cellular and molecular mechanisms involved in the uptake, retention, and elimination of Cd in target epithelial cells.
Cellular transporters control the uptake, distribution and elimination of drugs.
Kinetics of uptake, biotransformation, and elimination of parent compounds and metabolites were modeled with a first-order one-compartment model.
Kinetic rate constants were derived for all relevant processes: uptake, biotransformation, and elimination of parent compound as well as formation and elimination of the metabolites.
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