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Exact(10)
Zwitterionic structures were helpful for solubility, cellular uptake and activity for many drugs.
Muscular 99mTc-PYP uptake and activity gradient did not differ between PM and DM patients (data not shown).
The uptake and activity of the dansyl-labeled compounds were not dependent on the level of expression of CD4 at the cell surface.
To examine the effect of increased lipophilicity on cellular uptake and activity of CP, a lipoamino acid (2-aminododecanoic acid) was incorporated into peptide CP resulting in 2-aminodecanoyl-CP (LP).
Cell rounding of the cells was monitored by light microscopy as marker for toxin uptake and activity.
Phalloidin staining showed actin cytoskeletal disorganization in the toxin-treated cells confirming TcdB-LF fusion protein uptake and activity (not shown).
Similar(49)
We conclude that differences in DMBA uptake and activation or activity did not account for the resistance of EPI−/− mice to chemical carcinogenesis.
RAB7 knockdown did not influence heparanase uptake, processing and activity.
We conclude that sulfation of the tested flavonoids reduces their antiradical activity, and affects their cell uptake and biological activity in vitro.
The photophysical, photochemical, cellular uptake, and (photo cytotoxic activity of these complexes are described and discussed.
Silver nanoparticles (AgNPs) induced size-dependent adsorption, uptake, and hemolytic activity in Carassius red blood cells (RBCs) [9].
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