Sentence examples for uptake and activation of from inspiring English sources

In this study we sought to address this challenge by deleting arcA and ompR, two global regulators with the capacity to inhibit the uptake and activation of exogenous fatty acids.

To determine if increased allergen uptake and activation of mDCs (A/J mice) or pDCs (C3H mice) observed following intratracheal sensitization resulted from a greater overall recruitment of the dominant DC subset to the lung, we examined the number of total mDCs and pDCs in the lungs of A/J and C3H mice at 24 and 72 hours after HDM sensitization.

Oligopeptides stimulate GLP-1 secretion through PEPT1-dependent electrogenic uptake and activation of CaSR.

Our study is with agreement with previous study demonstrating stimulation of glucose uptake and activation of AMPK in rat muscle cells [ 78].

Besides the uptake and activation of acetate, the reactions of the glyoxylate shunt are necessary to replenish the tricarboxylic acid cycle.

The critical factors of the liposomes for uptake and activation of APCs, for example, carbohydrate density and particle size, remain to be elucidated.

Modulation of NA concentration in the synaptic cleft is mediated by a combination of re-uptake and activation of prejunctional α2-adrenceptors.

This body of work has demonstrated that biomaterial properties alter lymphatic transport, DC uptake and activation, activation of inflammatory pathways (e.g., toll-like receptors (TLRs) and inflammasomes), and secretion of signaling proteins called cytokines (9, 18– 318.

The authors found that LL37 protects NET DNA against extracellular degradation while enabling DNA uptake by and activation of pDCs via TLR9 engagement, leading to IFN-α production.

Several processes are responsible for these adverse changes including impaired calcium cycling, myocardial insulin resistance, increased lipid uptake, glucotoxicity, and activation of the renin-angiotensin-aldosterone system observed in mouse models of dilated cardiomyopathy (Table 2) (20).

Of note, these early guinea pig studies revealed the importance of vaccinating with live tumor cells, suggesting either a) the direct involvement of the tumor cells themselves in antigen presentation or b) the importance of prolonged expression and release of TAA to allow for sufficient uptake by and activation of immune effector cells.