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When selecting a neighbor, the neighbor must not be a node in the upstream route path.
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The activity of the upstream routes is encoded by a binary input parameter which indicates that the route is either active or not.
Possible upstream routes and central candidates for mitochondria-mediated apoptosis that are targeted by typical cancer agents include the pro-apoptotic factor p53 and Bcl-2 family of proteins.
The pathway can be triggered by using an NaCl shock and is activated via two parallel upstream signaling routes.
From there it was back on to the bikes to complete the route upstream - and then we all turned round and headed back to Exeter in time for a cup of tea at one of the many quayside cafes.
One of the main protective measures to be adopted in case of fires in road/rail tunnels is represented by suitable longitudinal ventilation systems being able to avoid fire and smoke exposure of humans, and to create a safe route upstream for evacuation.
In the last case study, there is capacity constraint at upstream of alternate routes.
Trout are more common upstream of the Pennsylvania Route 239 crossing of the creek than downstream of it.
Initial reports at the start of the year suggested a crossing between Tilbury and Gravesend, replacing a ferry service, but this had been rejected by July in favour of a route further upstream, near Dartford.
Therefore it is of key importance to reserve escape routes, in upstream of the fire source and cross passages, clear of the poisonous substances by supplying fresh air to the cross passages and the tunnel in which the train on fire draws up simultaneously.
These cases were selected because they helped cover the diversity of UNICEF education portfolio in Cambodia and helped identify the multiple routes to upstream work adopted by it.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com