Sentence examples for upstream role from inspiring English sources

If this induction of aura can be confirmed, it will indicate that this neuropeptide has an upstream role in CSD [191].

Therefore, given that more RPCs at P0 are generating postmitotic daughter cells and p27Kip1 is involved in cell cycle exit in the retina [31], perhaps Foxo3a plays an upstream role in the decision to generate a postmitotic daughter cell.

Although ligation of other integrins can either inhibit or promote the ability of α2β1 to bind collagen and, hence, signal [35] [37], an upstream role for the actin cytoskeleton has not been assessed for activation of collagen-binding integrins.

However, another report argues against an upstream role for siRNAs.

This approach has enabled UNICEF to move into an increasingly upstream role. 5.

Bid knockdown prevented loss of Δψm in both the amplification and the initiation phase, thus proving its upstream role.

It is interesting to note that in both phenotypes, we find genes with positive DoS values play crucial upstream roles.

Cells in other assays of SCAR/WAVE function are unlikely to have been exposed to as many apoptotic corpses as hemocytes are during development; alternatively upstream roles in phagocytosis may have hidden downstream functions of SCAR in processing.

In our model, SLC4A5, SLC5A10 and LDOC1 belong to such a type suggesting that sodium/bicarbonate transport, sodium/glucose transport and cell-proliferation regulation may play important upstream roles in pathogenesis of hypertension.

Identification of SLC4A5, SLC5A10 and LDOC1 indicated that sodium/bicarbonate transport, sodium/glucose transport and cell-proliferation regulation may play important upstream roles and identification of BNIP1, APOBEC3F and LDOC1 suggested that apoptosis, innate immune response and cell-proliferation regulation may play important downstream roles in hypertension.

Studies in zebrafish also reveal essential upstream roles for the VEGF system: high-dose morpholino knockdown of VEGF-A in early zebrafish embryos (day 2) results in a near-total absence of vasculature (similar to results in mice), whereas lower dose VEGF-A knockdown results in severe disruption of the dorsal aorta and intersegmental arteries (Nasevicius et al, 2000; Lawson et al, 2002).