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Scale bar of upstream regulatory fragments = 500 bp.
As a test of the implication of upstream regulatory transcription factors, SREPB genes were also studied.
Figure 3 Hypothetical and simplistic models of upstream regulatory information content of spatio-temporally regulated genes of rice.
Some differences may affect coding sequences, while others may occur in upstream regulatory regions and influence gene expression.
ATRA can reprogram the epigenetic landscape in the upstream regulatory region of ZMYND8 thereby promoting its expression.
Dissecting the upstream regulatory architecture of rice genes and their cognate regulator proteins is at the core of network biology and its applications to comparative functional genomics.
Consistently, mutations or loss-of-function of upstream regulatory genes, such as tuberous sclerosis complex 1/2 (TSC1/2), have been linked to cancer initiation and development [43].
Compared to the extensively studied regulations of the mTORC1 complex, the upstream regulatory signaling pathways governing mTORC2 activity remained largely to be determined.
For Cnox-5 we suggest a more upstream regulatory function.
Deregulation of Rho/ROCK pathway may be consequentially related to its aberrant upstream regulatory pathway.
In particular, it is not known if pathogens inhibit autophagy by modulation of upstream regulatory pathways.
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