Sentence examples for upstream regulating from inspiring English sources

A bill was passed in 1923 to enact the earlier plan of cutting through the dunes and adding an upstream regulating weir.

The promoter, the rho-independent terminator and a putative upstream regulating sequence (URS) show extensive sequence similarities.

In the AMPK Signaling pathway the gene expression of the upstream regulating kinases of AMPK, i.e, CAMKK, LKB1, MO25 and STRADA, were significantly up-regulated.

Examination of the tyrosine phosphoproteome of the Lkb1 deleted LC cells by MS analysis showed a critical role for Src activation, as the majority of differentially phosphorylated proteins upon Lkb1 deletion had this kinase as an upstream regulating kinase.

To further explore the DKK1 pathway in the cisplatin-refractory phenotype of NSCLC cells and to delineate putative mechanisms, Ingenuity Pathway Analysis (IPA) was used to map upstream regulating and downstream proteins of DKK1 (Fig.  4).

The modified pUC19 vector was constructed by generating NcoI and NotI sites at the terminal ends of the pUC19 wild-type TEM-1 gene sequence by site directed mutagenesis (QuickChange Mutagenesis) to allow the wild-type TEM-1 gene to be deleted (leaving the original upstream regulating sequences intact).

TGFβ upstream regulates many pathways.

Therefore, the identification of genetic targets may at times be beyond the domain of central metabolic fluxes, which themselves are upstream regulated along with the productivity phenotype.

The dynamic expression of HSPs during the spermatogenesis is upstream regulated by the heat shock transcription factors (HSF) [ 44], whose impairment has been linked to severe male reproductive defects [ 45, 46], including the pathogenesis of idiopathic azoospermia in human [ 47], a condition of severe male infertility due to unknown causes.

Together, these results suggest i) an upstream role for CASP2-mediated ROS regulation in modulating autophagy and ii) AMPK activation as an upstream event regulating the activation of MTOR and MAPK1/3 during CASP2-regulated autophagy.

However, the extent to which spindle orientation controls division symmetry or cell fate, and the upstream factors regulating this process, are still elusive.