The non-coding portion immediately upstream of the coding region presumably includes the coding exon acceptor site, as well as translation regulatory signals.
A second prominent homology peak is generally observed near the 5' end of the block, well upstream of the coding region and upstream of intervening low-homology non-coding sequence.
They may bind directly to special "promoter" regions of DNA, which lie upstream of the coding region in a gene, or directly to the RNA polymerase molecule.
SNPs distributed within 2.0 Kb upstream of the coding region were identified as promoter SNPs.
The candidate 2-kb upstream of the coding region of LOC_Os05g02730 was amplified using listed bisulfite primers (Table 3).
This 27-bp InDel is located about 28.3 kb upstream of the coding region of Pi2/Piz-t (Fig. 1a).
Ribosomes are often recruited for translation by a sequence closely upstream of the coding region [8].
In conclusion, we identified 1457 putative TSSs with promoter elements or with multiple identical sequences upstream of the coding region.
Microdeletions found 1 Mb 5' upstream of the coding region also displayed the same phenotype, suggesting that cis-regulatory elements might be present in that region.
There are large evolutionarily conserved regions both upstream of the coding region, but also in intron 1 of the ATXN2 gene.
A TRβ binding site upstream of the coding region of myelin associated glycoprotein was demonstrated to be TH-responsive using a luciferase expression system.
