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The phrase "upstream of the" is grammatically correct and can be used in written English.
It is typically used to describe a location or position that is located in the direction of the source of a river or stream. Example: The town is located upstream of the dam, making it vulnerable to flooding if the dam were to break.
Exact(60)
There had even been eels in Albuquerque fifteen hundred miles upstream of the Gulf of Mexico.
Upstream of the zoo, dozens of houses had been washed away while residents were asleep.
The researchers studied a 100km river catchment in the New Forest, upstream of the town of Brockenhurst.
The rescue and salvage efforts are being run from a massive barge tethered a few kilometres upstream of the wreckage.
The switch is surrounded by genetic sequences that match those found upstream of the EPO gene on the chromosome.
However, all the beaver dams remained standing upstream of the floods during July and more recent flooding.
Upstream of the dam, he said, lies "classic alewife territory," the kind of headwater ponds where alewives spawn.
At the upstream of the kasria.
Primers designed upstream of the initiation codon amplified the insertion.
site three (upstream of the Ammer lead-in).
0.5 kb upstream of the transcription start site.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com