Sentence examples for upstream loci from inspiring English sources

Only 2 types of epistasis exist based on functional relationships between or among loci (Table S4): epistasis between alleles at upstream loci and their regulated downstream loci (type I in scenarios 3, 4), and epistasis between alleles at different segregating loci within the same unit in each level of the system (type II in scenarios 5 7).

Second, positive selection in the direction of the pathway effect will result in 2 types of weak positive linkage disequilibrium (LD), one between the upstream loci and their regulated downstream loci (type I, scenarios 3 and 4) and between different segregating loci within the same units in each level of the signaling pathway (scenarios 5 7).

In scenarios 5 7 represent more complicated situations in which one or more loci at 2 (S and T) and 3 levels (S, T and B) of the signaling pathway are segregating such that both types I and II FD exist between downstream and upstream loci, and between different segregating loci within FGUs.

Contig 4108 included a single β-tubulin and upstream loci that showed conserved synteny with chromosome 21.

Notably, the increased expression of ORF transcripts in the rrp6Δ mutant is not due to defects in transcription termination from upstream loci, as the upstream expression level (defined as −100 to TSS) from these ORFs correlates poorly with the downstream expression levels (defined as TSS to +100).

Second, the chicken β-globin gene domain contains an internal enhancer element in addition to the upstream locus control region [ 12].

Homologous sequences were identified and tiled together to complete the T. congolense homolog to the upstream locus; this showed 67% identity to the T. brucei gene.

After locating a homolog to the upstream locus in L. major (LmjF21.1855) and tiling downstream, the 5'UTR of a β-tubulin gene was identified; this confirmed the presence of an ortholog to the chromosome 21 locus.

Under negative selection, i.e. in the opposite direction of the pathway effect, only null mutant alleles or repressors at upstream regulatory loci are responsive to selection and significant amounts of allelic diversity will remain at downstream loci.

This approach allowed us to identify upstream genetic loci that influence functioning of these specific miRNA and downstream gene expression and behavioural correlates which may be influenced by the same loci.

Cp occurs just upstream of locus 17 and the C1 non-coding exon is within locus 17.The first copy of Wp overlaps locus 21, which also contains W0.