Sentence examples for upstream growth from inspiring English sources
This momentum, along with its advantaged upstream growth portfolio, leaves us seeing BG as one of the most compelling investment opportunities in the integrated space.
Colorectal cancer (CRC) growth and progression is frequently driven by RAS pathway activation through upstream growth factor receptor activation or through mutational activation of KRAS or BRAF.
Initiatives like this also contribute to a bigger upstream growth: the farmers start selling their stuff, which they previously couldn't sell.
The available expression data indicate that GIPC1 is highly expressed in every human cancer and our results suggest GIPC1 is a necessary component for human cancer growth promoted by upstream growth factors and their receptors.
Overexpression of wild-type or activated SRC mutants may induce phosphorylation of this broader subset of targets distinct from the substrates of endogenous c-SRC activated by an upstream growth factor receptor.
PI3K is regulated by its upstream growth factor receptor tyrosine kinases (e.g., EGFR family receptors).
We hypothesized that combined inhibition of upstream epidermal growth factor receptor and kinase domain region receptors with AEE788 and inhibition of the downstream mTOR pathway with RAD001 would result in increased efficacy against gliomas compared with single-agent therapy.
Using pharmacologic and genetic silencing studies, we show that Klotho attenuates oxidant-induced AEC mtDNA damage and apoptosis via mechanisms dependent on AKT activation arising from upstream fibroblast growth factor receptor 1 activation.
Akt1 plays a central role in a number of signaling processes, acting both downstream and upstream of growth factor and target of rapamycin-directed events.
Furthermore, we succeeded in explaining the majority of promoter responses to inhibition of the upstream epidermal growth factor receptor kinase quantitatively based on the promoter profiles upon inhibition of the two individual downstream signaling pathways.
Also, we cannot rule out the possibility that non-NMDA receptor activation on the axonal shaft located upstream of the growth cone triggers a signalling cascade that travels to the growth cone through the cytoplasm.
