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Almost all these peaks were associated with lower intensity peaks of TBP/SNAP50 binding a few kilobases upstream, evidence that they represent transcription initiation sites.
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A third must-do is to take a long-term view: the really big prize lies much further upstream, where compelling evidence is emerging of return on investment from public health programmes and work in schools, communities and housing.
Fifteen months later, persistent upstream hydronephrosis without evidence of lithiasis at unenhanced MDCT (not shown) led to performing unenhanced magnetic resonance (MR) urography.
Overall, these findings for major components of core autophagy machinery and upstream regulators provide evidence for a transcriptional decline in autophagy gene expression with age in human monocytes.
If the ORF contains a predicted protein and peptides map upstream, they are evidence for a 5' extension and new start site.
There is strong evidence for upstream action from the Diabetes Prevention Program DPPP).
Cases where S1,2 > S1,B, S2,B were interpreted as evidence of upstream gene conversion.
In [ 3], those undefined values were regarded as lack of evidence for upstream binding and assigned values of one.
Mounting evidence regarding upstream signaling regulators for IL-32 production has been accumulating in the literature [ 12, 17- 20].
Examination of the upstream signaling pathways provided evidence for postsynaptic activation of B2 receptors, G protein activation of phospholipase C, InsP3 synthesis, and calmodulin activation.
4. The importance of evidence for upstream work: one of the key gaps identified by the incoming Country Representative in 2008 was a lack of data to prove the state of the education sector.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com