Sentence examples for upstream endpoints from inspiring English sources

This arrangement solves the problem of defining the upstream boundary of the promoter, which is a troublesome reality of studying promoters with no discernible upstream endpoints.

To this end, a workshop, Moving Upstream: A Workshop on Evaluating Adverse Upstream Endpoints for Improved Decision Making and Risk Assessment, was held 16 17 May 2007 in Berkeley, California.

This may be particularly true if downstream markers of the effectiveness of resuscitation (i.e. lactate, base deficit, pHi/PslCO2) fail to normalize despite successful achievement of predefined target values for the upstream endpoints of resuscitation in goal-directed therapy (Fig. 1).

A 2007 workshop, "Moving Upstream: A Workshop on Evaluating Adverse Upstream Endpoints for Improved Decision Making and Risk Assessment," brought together academic and government scientists to review relationships between chemical exposures, early biological effects, and later overt effects (Woodruff et al. 2008).

By enrolling this second cohort it was possible to estimate efficacy for a more upstream endpoint and to evaluate how it correlated with efficacy against clinical malaria in Cohort 1. Participants in Cohort 2 were followed up through both active detection of infection (ADI) and PCD.

Effectively serving as the bridge between the upstream and downstream endpoints of resuscitation, the microcirculation could be an attractive target for novel sepsis therapies.

Similarly, there is an alternative CNV endpoint 5 kb upstream of the common CNV endpoint.

Here and in the whole paper, the non-coding sequence of a gene includes the upstream sequences until the closer endpoint of the 5' adjacent gene, the intron sequences of this gene, and the downstream sequences until the closer endpoint of the 3' adjacent gene.

It is expensive and time-consuming to run experimental tests for all possible upstream process combinations in order to optimize the endpoint, rather it is much cheaper and faster to develop predictive models using computational intelligence (CI) which can be used as guidance tools in a competitive and rapidly changing environment.

The upstream sequence of M1 is the sequence from the closer endpoint of the 5' adjacent gene of M1 to the start codon of M1.

End of upstream gene model is the closer point of either start or endpoint of the transcribed region of the gene.