Exact(3)
In yeast, U-rich upstream elements are even more important than the NUEs for facilitating polyadenylation [ 29].
(E ) Conservation analysis of the Foxp3 locus finds that downstream and proximal upstream elements are conserved, whereas distal upstream genomic elements encoding the GAGE transcripts are not conserved.
Besides the more outstanding metabolic features that characterize tumour cells, other upstream elements are also important when describing the mechanisms of cell transformation.
Similar(57)
The sensor signal, i.e. the temperature difference between downstream and upstream elements, was more than 60 °C when the central heater was heated 300 °C above room temperature, which was comparable to a thin-membrane device modeled.
Pathway-specific upstream elements were also identified.
In contrast, the best sequence of plant far upstream elements is UGUA.
Interestingly, it has been demonstrated that C. reinhardtii and other green algae use a different set of poly(A) signals where the UGUAA motif in the near upstream elements is prevalent (found in 52% of the genes) over any other signals [ 16].
It is therefore plausible to assume that upstream promoter elements are more important for the quantitative modulation of Pepc transcription levels than the core promoter.
Deletion of the two proximal Zur boxes (pJEM- mptA8) abolished TPEN induced reporter activity, suggesting that additional upstream promoter elements are necessary for full mptA regulation.
Until recently it was thought that the NTS had no function, but studies of deletion mutants have shown that upstream control elements are required for the expression of 5S rDNA genes [ 4].
Furthermore, all dsx genes identified in this study showed male-biased expression levels, yet only half of the putative 5' upstream regulatory elements are preserved in D. magna and D. pulex.
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