Sentence examples for upstream border from inspiring English sources

Indeed, our results suggested that a site ~13 bp inside the upstream border of the +1 nucleosome is a sensitive regulation point in the yeast genome.

Interestingly, with the exception of H3 turnover, all of the properties present maximum signal peaks at ~-60 bp from the dyad of the +1 nucleosome (~13 bp from the upstream border of the +1 nucleosome).

Recent studies have shown that the +1 nucleosome significantly impacts gene regulation [ 5, 11, 31] and the TSS tends to be ~13 bp inside the upstream border of the +1 nucleosome [ 1, 2, 5- 7, 29, 41].

We found that by maintaining a distance of ~13 bp between the upstream border of the +1 nucleosome and the transcription start sites (TSSs), the stable +1 nucleosome may form a barrier against the accessibility of the TSS and shape an optimum chromatin conformation for gene regulation.

We then tested the hypothesis that the location ~13 bp inside the upstream border of the +1 nucleosome is an optimising chromatin conformation, which may achieve the maximum transcriptional outcomes while only requiring a minimal free energy cost for transcription elongation.

In addition, independent experiments have shown that there exists a genome-wide bias for the TSS location at a site ~13 bp inside the upstream border of the +1 nucleosome, indicating that the +1 nucleosome is very specifically positioned [ 3, 7, 8].

These regions possess the same upstream genome border located near an epsP synthase, and the downstream border near a tonB-dependent receptor, except for the xop10 element, where the downstream gene is located close to a methyltransferase.

Furthermore, the prediction of the structure of the upstream coil bordered by two cysteines remains to be addressed.

Hanford is about 25 miles from the Oregon border, upstream on the Columbia River.

A MAN-MADE spur juts into the mighty Jamuna river known as the Brahmaputra upstream, over the border in India near the town of Enayetpur.

Local officials accused neighbouring Burkina Faso of exacerbating the situation by opening the floodgates of a dam upstream from the border shared by the two countries.