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Additionally, we define an upper dose bound for PTV as (D_{1}^{mathrm{U}}> D_{1}^{mathrm{L}}) to avoid excessively high dose values inside the PTV.
A recommended dosing strategy is to start with a bedtime dose of 3 mg and then to increase the dose by 3 mg every four nights until pain relief is obtained, setting 24 mg as the upper dose limit.
Despite this, in our experiments, all upper dose limits for the OARs were decreased by subtracting 20-35 Gy from the typical dose values in normal IMRT cases for creating a higher quality IMRT plan.
In that system, high doses elevated inversions, but these were suppressed below spontaneous levels as the dose decreased below the upper dose threshold.
The upper dose limit for olanzapine is, in contrast to the other drugs, set above the label-defined upper dosage limit of 20 mg [ 31].
For patients with low body weight or poor general condition, doses can be decreased and upper dose limit can be set for the patient-controlled pump.
Two of the objective responses occurred in patients treated at the upper dose arm and lasted longer compared to objective responses that were achieved with the lower doses.
The matter of choice of upper dose limit has substantial impact upon the individual steps in the up-titration of the drugs.
The upper dose limit was 100 milli-osmolar because the assay could not discriminate active and inactive chemicals tested above this concentration.
The objective of this meta-analysis was to examine the effect of EPA+DHA, without upper dose limits and including food sources, on blood pressure in RCTs.
Although tumor incidence rates may strictly increase with dose, lifetime tumor rates may have an umbrella-shaped or a plateau-shaped dose response curve because of higher mortality in the upper dose groups.
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